Microplates have just launched a new product, the Microlute™ Protein Precipitation Plates. During biological sample preparation in the lab, the biological samples commonly contain proteins that interfere with downstream applications so Microplates created the Microlute™ Protein Precipitation Plates. This product uses the CRASH method, meaning the protein is denatured with acetonitrile and the flocculant filtered out, therefore allowing 96 samples to be handled at one given time.
Microplates explain that the protein ‘crashes’ out of solution. Hence, the reason the new product is called protein precipitation, is that the protein precipitates directly in each well when acetonitrile is added.
As mentioned, this is a new product offered by Microplates, and with this product comes many benefits. One main advantage is that it can solve all common problems associated with the CRASH technique of protein clean-up.
One common problem is that there can be leakage involved with samples. But with the protein precipitation filter plate, its novel dual filter (also known as the frit) and hydrophobically treated matrix, there will be no leakage of the sample through the plate before the application of vacuum.
As well as this new product they are offering, Microplates have optional drain cap and top cap mats available for those wishing to use vortex sample mixing.
Microplates have three available protein precipitation plates on their site, and the first PP plate is the P3 Protein Precipitation Plate High Efficiency (untreated frits) packed individually rigid shell. The well shape is square, and the volume is 2ml, and it is made of polypropylene.
Then you have the P3 Protein Precipitation Plate packed individually in a rigid shell and the P3 Protein Precipitation Plate – bulk packed in a bag of five, no individual shells. Each one of these PP filter plates is made up of Vyon HDPE for its filter material, and it has a long filter drip director. However, the first comes in rigid shells, whereas the bulk packed one consists of a bag of five with no individual shells.
Microplates have even provided a video about biological sample preparation with the Protein Precipitation Plate P3 in the Porvair Sciences research facility. This video is handy as it gives an overview of the new product by preparing a sample of serum for analysis by LCMS, and this requires a professional to remove some of the protein that would usually block up the columns in the liquid chromatograph, and they do this with the new PP plate.
From the video, you will see how quick and efficient Microplates new product is at helping you prepare your biological samples for analysis by LCMS.
You must get in touch with Microplates today and enquire about their new product – Protein Precipitation Plates. The Microlute™ Protein Precipitation Plates was created to provide you with the most benefits and to avoid any leakage of your samples in the lab.
Check out the pp filer plate online at https://www.microplates.com/protein-precipitation-plates/ where you can read more about each PP filter plate, download protocol, application note and also watch the uploaded video about the new product. If you have any questions or queries about the latest product, you can send an email to [email protected] or call +44 (0)1978 661144.
Porvair Sciences, specialists in the manufacture of microplate products, serve Life Sciences, Biotechnology, R&D and Molecular Biology with microplate solutions for all applications, from sample preparation to high throughput screening via our global distributor network.
Contact MicroplatesClywedog Road South
Wrexham Industrial Estate
+44 (0)1978 661144